NEJM -- Clinical pharmacodynamics of high-dose methotrexate ...
Original Article from The New England Journal of Medicine -- Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. Identification of a ...

Clinical pharmacodynamics of high-dose methotrexate in acute ...
Clinical pharmacodynamics of high-dose methotrexate in acute lymphocytic leukemia. ... High-dose methotrexate (500 to 33,600 mg per square meter of body-surface area) ...

Blood -- Pharmacokinetics and Pharmacodynamics of Oral ...
Pharmacokinetics and Pharmacodynamics of Oral Methotrexate and Mercaptopurine in ... One hundred ninety-one methotrexate doses and 190 mercaptopurine doses were ...

ATIC [PharmGKB]
Rheumatoid arthritis patients taking methotrexate (MTX) >3 months who carry the ... Folate pathway gene expression and methotrexate pharmacodynamics. PD. PK. FA ...

AMT [PharmGKB]
PD Pharmacodynamics & Drug Responses. PK Pharmacokinetics ... Folate pathway gene expression and methotrexate pharmacodynamics. PD. PK. FA ...

News - Pharmacokinetics Of Low-Dose Methotrexate Correlated ...
... of low-dose intermittent methotrexate are strongly correla ... "Pharmacokinetics and pharmacodynamics of low-dose methotrexate in the treatment of psoriasis. ...

Folate pathway gene expression differs in subtypes of acute ...
... of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics ... Methotrexate (MTX) is a major component in all contemporary treatment protocols ...

Methotrexate
Methotrexate may cause renal failure, gastrointestinal toxicity, or bone ... Methotrexate penetrates slowly into 3rd space fluids, such as ... Pharmacodynamics ...

Medline ® Abstract for Reference of 'Therapeutic use of high ...
UpToDate, electronic clinical resource tool for physicians and patients that provides information on Adult Primary ... Clinical pharmacodynamics of high-dose ...

Gene polymorphisms in folate metabolizing enzymes in adult ...
Despite its clinical success, methotrexate can be associated with serious ... of acute lymphoblastic leukemia and influences methotrexate pharmacodynamics. ...

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