omegajb24 replied: "Notice the only person that cited an actual source was Colby. Colby is right.
I have been taking Amoxicillin at least once a year for my entire life due to frequent sinus infections. Some times I did not drink on the pills and other times I did. There was no difference in their effectiveness. I have talked to my Dr. about this and she told me that it is a common myth. Some antibiotics do in fact interact with alcohol but Amoxicillin is not one of them. It will not kill you and will not diminish its effectiveness.
If there were a chance that it would kill you by mixing it with alcohol don't you think it would be put somewhere on the label or pamphlet? At least on my prescription I don't see such a label.
Drinking a little Bailey's with your hot chocolate is not a big deal and should be a decision made between you and your parents. If they are ok with it every once in a while it isn't going to cause you any harm in moderation.
Don't listen to clowns that just go on what some other clown told them."